Keene is a city in Cheshire County, New Hampshire, United States. Keene is most easily accessible by taking I-91 in Vermont to Exit 3 and getting on VT-9 in Brattleboro and heading into the traffic circle until VT-9 continues and follow it over a small bridge into New Hampshire (VT-9 becomes NH-9). Follow NH-9 about 15 miles to Keene. From the east, Keene is accessible via NH-101. NH-9 also connects Keene to Concord to the northeast.